In the movie, the Smurfs are trying to escape Gargamel and stumble through a portal to Central Park. Voices include Jonathan Winters as Papa Smurf, George Lopez as Grouchy, Fred Armisen as Brainy, Paul Reubens as Jokey, and Katy Perry as Smurfette. Hank Azaria plays a live-action Gargamel.
Yahoo! Movies article.